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Comparison of neuraminidases of the same subtype but from different species using a new method of titration

Identifieur interne : 000303 ( France/Analysis ); précédent : 000302; suivant : 000304

Comparison of neuraminidases of the same subtype but from different species using a new method of titration

Auteurs : B. Fiszon [France] ; C. Hannoun [France]

Source :

RBID : ISTEX:FB607767D382D4F3B0C37AA73D90A67B95B4A589

English descriptors

Abstract

Abstract: Neuraminidase is one of the two surface glycoproteins of influenza virions. In order to compare neuraminidases of the same subtype but isolated from different species (man, birds, pig), a new and simple method was adapted and optimized using peanut hemagglutinin. Results were very similar to those obtained with the classical method recommended by the WHO, using fetuin as a substrate. The technique was used to examine the relationship between animal and human neuraminidases belonging to serotypes N1 and N2. The resulte confirm the possible role of ducks as a reservoir for influenza viruses and the eventuality of interspecific exchanges.

Url:
DOI: 10.1016/0166-0934(90)90148-9


Affiliations:


Links toward previous steps (curation, corpus...)


Links to Exploration step

ISTEX:FB607767D382D4F3B0C37AA73D90A67B95B4A589

Le document en format XML

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<div type="abstract" xml:lang="en">Abstract: Neuraminidase is one of the two surface glycoproteins of influenza virions. In order to compare neuraminidases of the same subtype but isolated from different species (man, birds, pig), a new and simple method was adapted and optimized using peanut hemagglutinin. Results were very similar to those obtained with the classical method recommended by the WHO, using fetuin as a substrate. The technique was used to examine the relationship between animal and human neuraminidases belonging to serotypes N1 and N2. The resulte confirm the possible role of ducks as a reservoir for influenza viruses and the eventuality of interspecific exchanges.</div>
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{{Explor lien
   |wiki=    Sante
   |area=    H2N2V1
   |flux=    France
   |étape=   Analysis
   |type=    RBID
   |clé=     ISTEX:FB607767D382D4F3B0C37AA73D90A67B95B4A589
   |texte=   Comparison of neuraminidases of the same subtype but from different species using a new method of titration
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